Muscadine is an unincorporated community in Cleburne County, Alabama. It is near the Alabama-Georgia state line. Muscadine is 2.75 miles (4.43 km) east of Fruithurst. Muscadine has a post office with ZIP code 36269, a general store, and a bar.
Muscadine was an incorporated community for a time and was listed on the U.S. Census from 1890 to 1930. It peaked at 132 persons in 1900.
Photo by: Tracie Sims